You may be able to find testimonials online from people who take Zetia. Zetia isnt a statin drug. They can give you tips on how to deal with any side effects that may be bothersome. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Crestor, or with both drugs (when taken individually). Talk with your doctor if you have questions about using Zetia to lower your triglyceride levels. Taking Zetia with a statin may cause this side effect. Also, if you have a history of heavy drinking or liver damage, be sure to tell your doctor before you begin taking Zetia. joint or muscle pain*. Side effects could occur in children who are breastfed by someone taking a statin drug. Your doctor may do liver function tests before you start treatment and regularly during your Zetia treatment. You may experience muscle problems as a side effect of Zetia. Last medically reviewed on September 18, 2021. Statin drugs may pass into breast milk. To determine whether you have high cholesterol, your doctor will do a blood test called a lipid panel. . Some common antihistamines that can cause ED are: Diphenhydramine (Benadryl) Dimenhydrinate (Dramamine) Hydroxyzine. Healthline Media does not provide medical advice, diagnosis, or treatment. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. Examples of bile acid sequestrants include: Zetia inhibits the intestinal absorption of cholesterol and phytosterols, resulting in a decrease in the transport of intestinal cholesterol to the liver. Have your doctor measure your heart rate sitting and standing. You can also ask your pharmacist for information on how to dispose of your medication. These can be signs of rhabdomyolysis (muscle breakdown), which is a serious medical condition. I take pravastatin 80mg with absolutely no problem. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about . If you have side effects of Zetia that bother you, talk with your doctor or pharmacist. After first three days stopped it for two days. Risk factors for muscle-related problems. This is because it isnt safe to eat grapefruit or drink grapefruit juice while using a statin. About Postural orthostatic tachycardia syndrome. Its also not known if the drug is safe to take while breastfeeding or whether the drug passes into breast milk. This is because every persons body responds differently to medications. The expiration date helps guarantee that the medication is effective during this time. Postural Orthostatic Tachycardia Syndrome (POTS) is a blood flow disorder that causes a sudden spike in heartbeat with no change in blood pressure when going from a horizontal or seated to a standing position. An increase in levels of liver enzymes doesnt usually cause any symptoms. In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. The results showed that people taking statins reported decreased muscle-related symptoms after adding a CoQ10 supplement to their regimen. Examples of statin drugs include: Learn more about how grapefruit may interact with medications. Would a lower dose of Zetia help to reduce my risk of side effects? If you have any questions about eating certain foods while taking Zetia, talk with your doctor. If you develop liver problems, you may be more likely to experience side effects with Zetia. Zetia contains the active drug ezetimibe. Symptoms can be mild or serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Some people with POTS also may have one or more . Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. And Zetia hasnt been shown to affect blood sugar levels in clinical studies of people with diabetes and people without diabetes. Its FDA-approved to treat certain forms of high cholesterol in adults and in children ages 10 years and older. The autonomic nervous system is in charge of all bodily functions that we don't have to think about, such as: The sympathetic nervous system is part of the autonomic nervous system. Zetia is approved to treat different types of high cholesterol. Muscle problems are common side effects of statin drugs. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. The cause of the disorder is unknown. But keep in mind that Zetia is used to reduce cholesterol levels in your blood. In fact, researchers have looked into using Zetia to treat hair loss due to a condition called alopecia areata. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Zetia is a brand-name drug that contains the active drug ezetimibe. Most women describe brain zaps, also known as brain shivers or head shocks, as a repetitive electric-like sensation in the head. Zetias effect on cardiovascular morbidity and mortality isnt known. For more information and to find out if youre eligible for support, call 800-727-5400 or visit the program website. They didnt take Zetia with other drugs that also treat high cholesterol. Specifically, Zetia is used along with a low-cholesterol diet to treat: Zetia is approved to treat these conditions in certain situations. For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. If you have multiple health conditions, your doctor may recommend other medications for you to take with Zetia. And taking it with Zetia and a statin likely wont cause any problems. Learn about the drugs dosage, forms, strengths. Additionally, a change in weight is not a listed side . People with this condition have high levels of LDL (bad) cholesterol. If you no longer need to take Zetia and have leftover medication, its important to dispose of it safely. This is not a complete list of side effects and others may occur. Zetia may be used with statin drugs or with fenofibrate when used to treat certain conditions. The following information is provided for clinicians and other healthcare professionals. The list below includes factors to consider. Taking Zetia with a statin drug may increase your risk of developing some mild or serious side effects. They often originate at the base of the skull and spreading on the back of the head and neck. They may have suggestions depending on your weight and health goals. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. Below are examples of these side effects. Avoid eating foods high in fat or cholesterol, or Zetia will not be as effective. You should also look for supplements from reputable manufacturers. In addition, Zetia may be used with fenofibrate to treat mixed hyperlipidemia. In studies, weight changes didnt occur in people who took the drug. See the Zetia prescribing information for details. Yes, treatment with Zetia should lower your triglycerides. In addition to Goff's specific symptoms, POTS can be associated with neurocognitive impairments or "brain fog"; problems with body temperature regulation; gastroenterological symptoms like nausea, abdominal pain, diarrhea, or constipation; and dark red-blue discoloration of the legs. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. These drugs havent been directly compared in clinical studies. Talk with your doctor about any liver problems you may have and whether its safe for you to take Zetia. Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain. * Sex and gender exist on spectrums. Statins lower cholesterol by preventing your liver from making new cholesterol. Zetia shouldnt cause weight gain or weight loss. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. Zetia can cause muscle-related side effects. Zetia is also available in a generic form called ezetimibe. Clinical studies have shown Zetia to be effective for treating primary high cholesterol when used alone or with statin drugs. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. weakness and fatigue (tiredness) headaches. Your doctor might suggest one or more of these: fludrocortisone (helps the kidneys retain sodium) midodrine (causes the blood vessels to tighten) beta blockers (slow down the heart rate). However, it isnt known how Zetia may affect these risks. Learn more about some of the side effects that Zetia may cause. Zetias side effects are usually mild, especially if youre taking Zetia alone. Statins, another medication for high cholesterol, are known to cause muscle-related side effects. They can tell you about other medications that may work well for you. Plant sterols are similar to cholesterol. You can take Zetia at any time during the day, but try to take your dose around the same time each day. Before starting a new medication, its a good idea to talk with a healthcare professional about any questions or concerns you may have. Talk with your doctor right away if you have fever or chills with your joint pain. If youre pregnant or breastfeeding, or if youre planning to become pregnant or breastfeed, tell your doctor. Learn more about how grapefruit may interact with medications. Typical symptoms of POTS include: heart palpitations (feeling your heart beating or racing) dizziness or lightheadedness. For more information about how the drug is used, see the Zetia uses section below. Your doctor may prescribe Zetia with a statin drug. But the condition isn't well understood, and many patients are dismissed as having anxiety, delaying diagnosis. Talk with your doctor about your health history before you take Zetia. This helps prevent others, including children and pets, from taking the drug by accident. Tell your doctor if youre experiencing bothersome side effects from Zetia. Uses. Another is trouble standing up, primarily because not enough blood returns to the heart upon standing, which causes a rapid increase in heart rate called tachycardia. It can also interact with certain supplements as well as certain foods. Medications in the fibrate drug class are used to treat high cholesterol. Study on Ezetimibe Yielded Disappointing Results: Another reader wrote us shortly after learning of the results of a study that raised questions about ezetimibe: Q. This drug has not been studied in pregnant females.*. Zetia is sometimes used with medications in the statin drug class. Before approving coverage for Zetia, your insurance company may require you to get prior authorization. However, skip your missed dose if its almost time for your next dose. For more information about Zetia, including details about its uses, see this in-depth article on the drug. POTS-related fatigue is physical in nature . Youll also need to check your insurance plan, as it may only cover one or the other. People who may be at higher risk of this side effect include those who: Tell your doctor if any of the above apply to you before starting Zetia treatment. Talk with your doctor about the risks of taking Zetia with warfarin. Zetia is sometimes used with medications in the statin drug class. (For information on side effects, see the Zetia side effects section above.). If your doctor has prescribed Zetia and youre interested in using ezetimibe instead, talk with your doctor. What are the serious side effects of Zetia? The dose of Zetia used for children is the same as the adult dose. Then you can share this information with your doctor. But over time, heavy alcohol use can damage your liver. Below are examples of these side effects. Zetia may be used with statin drugs to treat the following conditions in adults: Statins are another class of medications used to lower cholesterol. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. The absence of symptoms doesn't necessarily mean that the cause of POTS is gone as well. Zetia is available in a strength of 10 milligrams (mg). Read on to find out more about healthy cholesterol levels, and if a cholesterol level of 250 ml/dL is considered, Heart disease is a top cause of death in the U.S. The manufacturer of Zetia hasnt stated whether the tablets can be crushed, split, or chewed. Or they may recommend that you stop taking the medication. Total cholesterol is the overall amount of cholesterol found in your blood. Read more about how inherited high cholesterol affects life expectancy and what makes it different from regular hypercholesterolemia. But if they become more severe or dont go away, talk with your doctor or pharmacist. These lists contain examples of serious side effects that can occur with Lipitor or with both drugs (when taken individually). These tests will look at your cholesterol levels and also your liver enzyme levels. If your muscle-related side effects dont go away or become severe, tell your doctor right away. Medications in this class prevent your small intestine from absorbing cholesterol. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. So stopping Zetia may lead to an increase in your cholesterol levels. This included relief of muscle pain, muscle weakness, and cramps. muscle pain while taking ezetimibe with a statin. Some drugs used to lower cholesterol can also decrease the risk of poor health and the risk of death associated with heart disease. (Primary hyperlipidemia is also called primary high cholesterol.) Before taking Zetia, talk with your doctor about your health history. During your Zetia treatment, consider keeping notes on any side effects youre having. Currently GARD aims to provide the following information for this disease: Population Estimate: This section is currently in development. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. sinusitis. These lists contain up to 10 of the most common mild side effects that can occur with Zetia, with Lipitor, or with both drugs (when taken individually). upper respiratory tract infection, including the common cold. Zetia is indicated as an adjunct to a low-cholesterol diet for treatment of the following types of hyperlipidemia: For treatment of primary hyperlipidemia, Zetia is indicated to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (non-HDL) cholesterol, and apiloprotein B (ApoB). Fatigue. It can cause mild side effects and, less commonly, serious side effects. A life-changing condition called POTS, which can cause fainting, irregular heartbeats and dizziness, particularly among young women, appears to be on the rise as a result of the coronavirus pandemic. Read more about these alternatives to traditional statin, Having high cholesterol puts you at risk for a heart attack or stroke. If you use Zetia and warfarin together, your doctor may want to monitor you more closely during your treatment. Zetia contains the active drug ezetimibe. Allergic reaction. Some people witness mild symptoms, some have a big impact on their lives due . The generic is considered to be as safe and effective as the original drug. Qu H, et al. Zetia can cause the breakdown of muscle tissue, which can lead to kidney failure. Before taking Zetia, talk with your doctor and pharmacist. POTS is a kind of dysautonomia or autonomic nervous disorder. These symptoms can be signs of an infection. There are no known interactions between Zetia and alcohol. Muscle-related problems are a possible side effect of Zetia when used with other medications. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. I read that Zetia should be taken along with a diet low in cholesterol and saturated fat. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Physicians who treat dysautonomia can be located on our Physician List. (A class of medications is a group of drugs that work in a similar way.) Zetia can cause mild or serious side effects. Total cholesterol was reduced by 12% more in children who took Zetia and simvastatin than children who took simvastatin alone. (A class of drugs is a group of medications that work in a similar way.) Talk with your doctor about birth control options that may be best for you. Ways to reduce the symptoms. If you need financial support to pay for Zetia, or if you need help understanding your insurance coverage, help is available. Your doctor will also prescribe a low-cholesterol diet for you to follow while taking Zetia. In the video she posted on Thursday, the "Real Housewives of New York City" alum detailed her suffering from a severe dehydration issue and shared that her doctor . Its not clear if CoQ10 prevents muscle-related side effects when Zetia is taken with a statin, but it might help. There arent any foods that have been specifically reported to interact with Zetia. Generics tend to cost less than brand-name drugs. These conditions can raise your risk of muscle problems while taking Zetia. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. While taking Zetia, tell your doctor right away if you experience extreme muscle pain, muscle tenderness, or dark-colored urine. If youve had an allergic reaction to Zetia or any of its ingredients, you should not take Zetia. * To learn more about this side effect, see the Side effects explained section below. Serious side effects from Zetia arent common, but they can occur. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. However, several medicines can be prescribed off-label when needed. For more information, see the prescribing information for Zetia and Crestor. Tramadol will usually cause a blistering type rash with itching which you do not describe. Zetia may not be right for you if you have certain medical conditions or other factors affecting your health. 2. Yes, there are a few. This can increase your risk of side effects from either medication. diarrhea. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. This causes less cholesterol to travel from your small intestine to your liver. Zetia contains the active drug ezetimibe. This may increase your risk of side effects. Symptoms of a swollen gallbladder may include: Tell your doctor if you experience gallstones while using Zetia with fenofibrate. This is a serious medical condition that, if left untreated, can lead to kidney damage. voice changes. The actual price youll pay for any of these drugs depends on your insurance plan, your location, and the pharmacy you use. Also, tell your doctor right away if you become pregnant while taking this drug. Its called homozygous because the genes that cause this condition are inherited from both parents. We talked to experts about, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Talk with your doctor or pharmacist if you have trouble swallowing Zetia tablets. Before trying something new, its common to look for written reviews about the experiences of others. (Fenofibrate is a drug used to lower your triglyceride levels.). * This is a partial list of mild side effects from Zetia. Here we look at how Zetia and Lipitor are alike and different. Learn about alternatives like new drugs, A new class of self-injectable medications are showing promise in treating high cholesterol. Fenofibrate is a drug used to lower your triglyceride levels. You can also call the American Association of Poison Control Centers at 800-222-1222 or use their online tool. Postural orthostatic tachycardia syndrome (POTS) is a blood circulation disorder characterized by two factors: A specific group of symptoms that frequently occur when standing upright. Using Zetia for high cholesterol. These drugs havent been directly compared in clinical studies. High cholesterol may be caused by genetics, smoking, low amounts of physical activity, or eating too many high-cholesterol foods. Drugs in this class prevent your small intestine from absorbing cholesterol. * For these purposes, Zetia and Crestor are used to treat people of different ages. The underlying cause is not known, although it sometimes follows bedrest after injury or illness. To help make sure you dont miss a dose, try setting a reminder on your phone. Here is a list of conditions that the Food and Drug Administration (FDA) has approved Zetia and Crestor to treat. (Mixed hyperlipidemia is also known as mixed high cholesterol.). Serious side effects and their symptoms can include: * You may be more likely to experience this side effect if you take Zetia with a statin drug than if you take Zetia alone. Get answers to some frequently asked questions about Zetias side effects. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about the change in her physical appearance. It isnt safe to eat grapefruit or drink grapefruit juice while using statins. Zetia is a prescription drug used to treat certain types of high cholesterol. We avoid using tertiary references. They can both be taken with or without food. Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. If youre concerned about joint pain while using Zetia, talk with your doctor. Side effects may be more likely in older adults. Lipitor is also FDA-approved for the following conditions when used with a low-cholesterol diet: primary dysbetalipoproteinemia in adults (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), liver complications, such as high levels of, Both Zetia and Crestor are FDA-approved to treat the following conditions* when used with a. Crestor is also FDA-approved for the following conditions in adults when used with a low-cholesterol diet: primary dysbetalipoproteinemia (a genetic condition that causes high total cholesterol, high triglycerides, and low HDL levels), pain on the right side of your body, below your ribs, in adults as monotherapy or in combination with an HMG-CoA reductase inhibitor (statin drug), in adults in combination with a fenofibrate, in combination with statins, in people with hepatic disease, in combination with statins, in people with elevated hepatic transaminases, in combination with statins, during pregnancy or in someone planning to become pregnant, in combination with statins, while breastfeeding, in people who have a known allergy to Zetia. Taking Zetia with cyclosporine (a drug that suppresses your immune system) can raise the levels of both medications in your body. If taking your dose at bedtime doesnt help, or if dizziness becomes severe, tell your doctor. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). This part of the nervous system controls functions that we don't actively control, such as heart rate, blood pressure, perspiration, and temperature. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. If your doctor recommends that you stop taking Zetia, they may suggest another treatment option for your condition. However, some people have reported experiencing memory loss when taking statin drugs. Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. Theyll guide you with suggestions they may have to relieve these side effects. The generic is considered to be as safe and effective as the original drug. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. Ezetimibe may cause side effects. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. Tell them about all prescription, over-the-counter, and other drugs you take. Crestor is available in a generic form called rosuvastatin. Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. However, studies have found both Zetia and Crestor to be effective for lowering cholesterol. yellowing of your skin or the whites of your eyes, ahajournals.org/doi/10.1161/JAHA.118.009835, organon.com/product/usa/pi_circulars/z/zetia/zetia_pi.pdf, Alternatives to Statins for Lowering Cholesterol. Absorption isnt affected by food. Medications in the statin drug class work differently than cholesterol absorption inhibitors like Zetia. . This can raise your levels of these drugs and increase your risk of side effects. Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug) and Zetia is a cholesterol -lowering drug. The effect of Zetia, atorvastatin, or simvastatin on other types of cholesterol levels in this study isnt known. Its not known if Zetia is safe to take during pregnancy. Your doctor will determine the best dosage to fit your needs. And some may be easily managed, too. In studies, some people had to stop taking Zetia because of this side effect. They may have a preference for one version or the other. Mild side effects of Zetia when taken with a statin (another kind of cholesterol -lowering drug) may include: infection, such as a respiratory . The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. We've provided a list of the best at-home tests for. Porphyria patients are often overly sensitive to sunlight. However, your doctor will check your cholesterol levels about 4 weeks after you start treatment. This in turn increases clearance of cholesterol from the blood. Covers lawsuits, malpractice, class actions, fraud, legislation, regulation, enforcement. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. dark colored urine. A generic drug is an exact copy of the active drug in a brand-name medication. It can develop suddenly or maybe over time. (2018). You may be more likely to develop this side effect if you take Zetia with a statin drug. They may be able to help determine whats causing your hair loss. While there's no cure, several treatments and lifestyle changes can help manage the symptoms of POTS. Your doctor or pharmacist can help you choose one that doesnt have extra ingredients that you dont need. Medications in the fibrate drug class may increase the amount of cholesterol thats stored in your gallbladder. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate. Clinical studies have shown Zetia to be effective for treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin. It wasnt reported during studies of the drug. Reverso Context ofer traducere n context din englez n romn pentru "but as in", cu exemple: Belgium overall has a good track record of achieving the nominal budgetary targets, but as in recent years a strict monitoring will be necessary to achieve the target for 2007.
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